ABC transporters in disease: ABCG2 contributes to the survival of hematopoietic and leukemic progenitors
| Dates: | 7 March 2014 |
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| Times: | 14:00 - 15:00 |
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| What is it: | Seminar |
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| Organiser: | Faculty of Life Sciences |
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| Who is it for: | University staff |
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| Speaker: | Prof John D. Schuetz |
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Prof. Schuetz works on the role of ABC transporters in response to chemotherapy, the biological function of ABC transporters and the regulation of ABC transporters. He is a Faculty Member at the world-renown St Jude Children’s Hospital in Memphis. Please contact Bob Ford (bob.ford@manchester.ac.uk) x64187 if you would like to meet with John on the 7th.
Krishnamurthy P, Du G, Fukuda Y, Sun D, Mercer K, Wang J, Sosa-Pineda B, Murti G, Schuetz JD. Identification of a mitochondrial porphyrin transporter. Nature 443:586-9, 2006.
Cheepala S, Hulot J-S, Morgan J, Zhang W, Naren AP, Schuetz JD. Cyclic Nucleotide Compartmentalization: contributions of Phosphodiesterases and ABC transporters. Annu Rev Pharmacol Toxicol 53:231-53, 2013
Zhang Y, Li F, Patterson AD, Wang Y, Krausz KW, Neale G, Thomas S, Nachagari D, Vogel P, Vore M, Gonzalez FJ, Schuetz JD. Abcb11 Deficiency Induces Cholestasis Coupled to Impaired ?-Fatty Acid Oxidation in Mice. J Biol Chem 287(29):24784-94, 2012.
Ulrich DL, Lynch J, Wang Y, Fukuda Y, Nachagari D, Du G, Sun D, Fan Y, Tsurkan L, Potter PM, Rehg JE, Schuetz JD. ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity. J Biol Chem 287(16):12679-90, 2012.
Fukuda Y, Schuetz JD. ABC transporters and their role in nucleoside and nucleotide drug resistance. Biochem Pharmacol 83(8):1073-83, 2012.
Speaker
Prof John D. Schuetz
Organisation: St Jude Children’s Hospital, Memphis
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Travel and Contact Information
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Lecture Theatre
Michael Smith Building
Manchester
GB
