Control of adult tissue repair by manipulating cell-extracellular matrix interdependence
| Dates: | 13 February 2014 |
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| Times: | 11:00 - 12:00 |
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| What is it: | Seminar |
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| Organiser: | Faculty of Life Sciences |
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| Speaker: | Takao Sakai |
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To facilitate tissue regeneration and remodelling, we need to understand local microenvironment (niche). Over the past 5 years, I have focused on how tissue regeneration and remodelling are regulated by local microenvironment. I have been particularly interested how we can, by manipulating microenvironment extracellular matrix (ECM) and TGF-? signalling, change the clinical outcome of the debilitating disease, liver fibrosis and tendon injury. Using animal models, developed in my laboratory, I have gotten several key findings in the field. I would like to present those findings and discuss future directions.
Speaker
Takao Sakai
Organisation: University of Liverpool
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1.006
AV Hill Building
Manchester
GB
